Nephrogenic Systemic Fibrosis Lawsuit Information
Gadolinium / Nephrogenic Systemic Fibrosis Background
Nephrogenic Systemic Fibrosis (NSF) is a medical condition that has come to be associated with exposure to the element gadolinium, when used as a radiocontrast agent during an MRI. The following links provide supplementary detailed information about NSF from both governmental and other resources. Please browse these resources in order to better understand NSF and its causes, and if you or anyone you know may have been exposed to gadolinium through any of these sources, please contact a gadolinium or NSF lawyer to provide counsel on any appropriate legal action.
What is Gadolinium?
Gadolinium is a metal that is silvery-white in color, and is used in a wide variety of applications including microwaves, televisions, nuclear marine propulsion systems, intravenous radiocontrast agents, and in other medical imaging applications. It is also known by various other names such as gadolinium-DPTA, gadodiamide, and its brand names such as Magnevist, Omniscan, and ProHance.
The Properties of Gadolinium
Gadolinium is a silvery white metal that is both malleable and ductile. It is relatively stable in dry air, but when exposed to moisture, it does tarnish quickly. It is soluble in dilute acids. An important property in terms of its applications is that it is also highly paramagnetic at room temperature, meaning that it will display magnetic properties when exposed to a magnetic field.
The Uses of Gadolinium
Gadolinium is used in a wide variety of applications including microwaves, television tubes, compact discs, and computer memory. It is also used in nuclear marine propulsion systems to slow down the initial reaction rate. Gadolinium is also used in a number of medical imaging applications including x-rays, magnetic resonance imaging, and positron emission tomography.
Although Gadolinium is generally considered safe, the use of it in MRI contrast media is now considered harmful for those with kidney disorders. This is because it can lead to nephrogenic systemic fibrosis, especially in patients with end-stage renal disease who are on regular dialysis treatment. Less than one in a thousand people may also be allergic to gadolinium containing substances.
What is Nephrogenic Systemic Fibrosis (NSF)?
Nephrogenic Systemic Fibrosis is a recently discovered disease that occurs in kidney patients. A strong correlation has also been found between NFS and gadolinium containing MRI contrast dyes. This disease affects the skin and results in tightening and swelling, and may cause contractures due to the thickening of the skin, limiting movement of the joints. A number of treatments have been tried and are being investigated, though none have proved consistently successful.
Who is at Risk of Contracting Nephrogenic Systemic Fibrosis?
So far, Nephrogenic Systemic Fibrosis has only been found in patients with kidney disease. Men, women, the old, and the young are all affected by this disease. Other factors that may be associated with Nephrogenic Systemic Fibrosis are coagulation abnormalities, deep vein thrombosis, recent surgery, or the failure of a transplanted kidney. Although the FDA has recently issued a warning about the possible link between gadolinium containing contrast dyes, there is as yet no proven cause and effect factor between these two, but strong correlations are shown.
Symptoms of Nephrogenic Systemic Fibrosis
Nephrogenic Systemic Fibrosis is a disease that develops over days or weeks and involves swelling, tightening, and thickening of the skin, which may also lead to contractures and make the movement of joints difficult, thus making it impossible for the patient to walk. The skin may also develop red or darkened patches, plaques, or papules and the patient may experience burning, itching, or severe pain in the area. The skin also develops an orange-peel texture and may feel woody.