Generic: Epoetin alfa
Manufacturer: Ortho Biotech Products, L.P.
Date approved: 1989
Status: Black box warning from FDA
Approved uses: Approved for the treatment of anemia in patients with chronic renal failure (kidney failure)
Off-Label uses: Treatment of non-renal anemia
• chest pain
• Patients with cancer can be at risk for life-threatening side effects and death
Procrit, manufactured by Ortho Biotech Products, is an erythropoiesis-stimulating agent (ESA) approved for the treatment of anemia in patients who have undergone renal failure and/or kidney transplant. In March 2007, the federal Food and Drug Administration (FDA) announced that Procrit and other ESAs are associated with a higher risk of death or life-threatening side effects in patients who have cancer. A new black box warning, “dear doctor letter” and prescribing information are pending.